| ncRNA name | rno-miR-1273g-3p |
| ncRNA Category | miRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Rattus norvegicus |
| Tissues/Cell_line | RPE cells |
| Methods | qRT-PCR, Western blot |
| Expression pattern | up-regulated |
| Functional description | miR-1273g-3p was highly expressed in STZ-induced DM RPE cells. miR-1273g-3p mimic promoted the expression of DR-related MMP-2, MMP-9, and TNF-α proteins, and ALP-related LC3, cathepsin B, and cathepsin L factors, but miR-1273g-3p inhibitor suppressed the levels of these factors. |
| PubMed ID | 29197896 |
| Year | 2017 |
| Title | miRNA-1273g-3p Involvement in Development of Diabetic Retinopathy by Modulating the Autophagy-Lysosome Pathway. |
| Drug-related ncRNA | NO |
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